87.00€

VitiDerm® topical gel

VitiDerm® topical gel

DermoPro latest innovation

Innovation with an optimized and more concentrated formula , VitiDerm ® gel ingredients helps to prevent oxydative stress that cause disruptions in normal mechanisms of cells.

Loss of melanin in melanocytes is a key factor in the symptoms of vitiligo.

VitiDerm® provides a formula with vitamins, amino acid and plant extract of melon (superoxide dismutase and catalase) that help to fight free radicals that cause cellular damage and which are harmful to melanocytes.

Ginkgo biloba and Vitamin D3 (calcium chloride) helps to a normal energy metabolism.

 

THE PYSIOLOGICAL CONDITIONS FOR PIGMENTATION

It has been shown that treatment with pseudocatalase, copper, and vitamin E help limits oxidative stress and help to a normal colored skin. (B)

 

CELL DAMAGE IN PATIENTS WITH VITILIGO

 

 Oxidative stress level and tyrosinase activity in vitiligo patients


 

VitiDerm

 

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Price in GBP : £ 70


Presentation : 100 ml tube Non-greasy, paraben-free gel to be applied morning and evening. Massage into clean, dry skin using light strokes.

Ingredients :  melon extract, Calcium chloride, Ginkgo biloba extract, vitamin D3...

VitiDerm in farmacy : Available from dispensing chemists: ACL 9968447

or order from our laboratoires throught this page

- Get the medical folder -

Bibliography and scientific references :

1/ Disruption of phénylalanime hydroxylase in a cycle dysfonctionement biopterin / 6-BH4. Epidermal H2O2 accumulation alters the cycle of tetrahydrobiopterin (6-BH4) of known importance in the early stages of melanin synthesis and catecholamine which are accompanied by a lowering of catalase.
Calcium intake and catalase reduces the levels of H2O2 and regulates the cycle of biopterin.
2/ Tyrosinase is the key enzyme of melanogenesis responsible for pigmentation. It loses its effectiveness in the presence of oxygen free radicals (superoxide ion O2-). The contribution of catalase and SOD, Ginkgo Biloba can reduce levels of O2-H2O2
3/Melanin bleached in the presence of oxygen radicals (. OH).
A contribution of catalase and SOD, Ginkgo Biloba can reduce levels .OH


(A) Karin U Schallreuter*,†, Jeremy Moore*, John M Wood*, Wayne D Beazley*, Eva M J Peters*, Lee K Marles*, Stefanie C Behrens-Williams*, Reinhard Dummer‡, Nenad Blau§ and Beat Thöny§
1.*Clinical and Experimental Dermatology, Department of Biomedical Sciences, University of Bradford, West Yorkshire, U.K
2.†Institute for Pigmentary Disorders e.V. in Association with the Ernst-Moritz-Arndt University Greifswald, Germany
3.‡Department of Dermatology, University Hospital, Zurich, Switzerland
§Division of Clinical Chemistry and Biochemistry, University Children's Hospital, Zurich, Switzerland.
(B) DRS DUGAS B, SIVAS V, FRANCES C, DEBRE P, Effet protecteur de l'association des Superoxydes Dismutases et de la Catalase végétales sur le développement inflammatoire associé au vitiligo chez l'homme.
(C) Successful treatment of oxidative stress in vitiligo. Clinical and Experimental Dermatology, Department of Biomedical Sciences, University of Bradford. Schallreuter KU. Skin Pharmacol Appl Skin Physiol. 1999 May-Jun;12(3):132-8 
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